Company news

20 May 2019

Alkor Bio Group of Companies has expanded the range of oligonucleotides, including custom-made

In mid-May, Alkor Bio Group of Companies, a developer and manufacturer of laboratory diagnostic reagent kits, announced a significant expansion of the range of oligonucleotides that it is ready to synthesize for third-party organizations. We are talking about the synthesis of simple and modified oligonucleotides, including probes for real-time PCR.

Leader of the oligosynthesis group in the molecular diagnostics laboratory Alexandra Perchik:

“For our own production - the development and production of kits for PCR diagnostics and biochips - we, starting from 2012, will synthesize oligonucleotides of good quality and in the required quantity. In 2013, when the technological scheme of such a synthesis was fully debugged, we began to accept orders from third parties as well. In total, the laboratory of molecular diagnostics produces 23 modifications of nucleotides, of which new ones are: LNA, Alkin, Cy3, Cy3,5, Cy5,5 and oligonucleotide probes Cy3-BHQ2, Cy3,5-BHQ2, Cy5,5-BHQ2. "

The synthesis is carried out on a new imported synthesizer MerMade 48X, the company invested about 10 million rubles in its acquisition. This equipment is distinguished by its high performance, which allows it to overlap the needs of its own production of Alkor Bio Group.

GC Alkor Bio is able to produce, that is, synthesize and purify, up to 100 oligonucleotides per day. These are oligonucleotides of standard quality, as required, for example, by PCR, and highly purified, suitable for the most subtle scientific experiments, for example, for cloning.


Oligonucleotides are short fragments of nucleic acids with a given sequence, which are obtained by chemical synthesis on automatic DNA synthesizers. Synthetic oligonucleotides are widely used in scientific research in the field of molecular biology and modern medicine, including in biochip-based technologies, for PCR diagnostics, for cloning, sequencing of the genome, as well as for the synthesis of artificial genes. Modified oligonucleotides are oligonucleotides containing, in their structure, in addition to standard nucleotide bases, other chemical fragments, for example, fluorescent labels. Probes for real-time PCR contain combinations of fluorescent labels and "quenchers" - molecules that can quench fluorescence.